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Description
Invivo Anti-Mouse CD11c Recombinant mAbProduct Specification Host Armenian hamster Antigen CD11c Synonyms Integrin alpha X; CD11 antigen like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax Location Membrane Accession Q9QXH4 Clone Number S R518 Antibody Type Recombinant mAb Application Functional assays Reactivity Ms Purification Protein G Concentration 5 mg ml Purity >95% (Determined by SDS PAGE) Endotoxin <1EU mg
Product Specification
| Host | Armenian hamster |
| Antigen | CD11c |
| Synonyms | Integrin alpha-X; CD11 antigen-like family member C; Leukocyte adhesion glycoprotein p150,95 alpha chain; Leukocyte adhesion receptor p150,95; Itgax |
| Location | Membrane |
| Accession | Q9QXH4 |
| Clone Number | S-R518 |
| Antibody Type | Recombinant mAb |
| Application | Functional assays |
| Reactivity | Ms |
| Purification | Protein G |
| Concentration | 5 mg/ml |
| Purity | >95% (Determined by SDS-PAGE) |
| Endotoxin | <1EU/mg |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, containing no preservative |
| Stability & Storage | 2 to 8 °C for 2 weeks under sterile conditions; |
Background
CD11c, also known as integrin alpha X (ITGAX), is a ~150 kDa type I transmembrane glycoprotein that pairs non-covalently with the 95 kDa beta2 integrin CD18 to form the αXβ2 heterodimer (complement receptor 4, CR4), which mediates cell adhesion, migration, and phagocytosis by binding diverse ligands such as iC3b, fibrinogen, ICAMs, and denatured proteins; it is predominantly expressed on myeloid dendritic cells, tissue macrophages, activated monocytes, and some B-cell subsets, serving as a classic marker for conventional dendritic cells in both mice and humans, and plays crucial roles in immune surveillance, antigen presentation, and inflammatory responses while also being implicated in autoimmune diseases and serving as a therapeutic target in cancer immunotherapy.
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4.4 ★★★★★
Based on 444 reviews
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Product Reviews
★★★★★ 4
Sam + Percy 💕
Format: Kindle
Every Summer After is a perfect summer read and although it had been in my TBR for so long, I really enjoyed it. I’m a sucker for second chance romance and childhood friends to lovers and I was captivated immediately. Their friendship blossomed into a cute young love romance until one impulsive decision during a vulnerable moment lead to the downfall of Sam & Percy’s relationship.
Now over a decade later, Percy makes the trip back to the lake to attend a funeral and memories flood back of her summers with Sam. But does time heal all wounds? Read to find out.
I really love young love romances because they are innocent with heighten emotions, personal growths and can be extremely messy. Not to mention the angst that keeps me wanting to read more and this book definitely kept me engaged.
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Reviewed in the United States on September 7, 2025
★★★★★ 5
Warm Blanket Read
Format: Paperback
Wow, I didn’t know how much I needed this and I inhaled it. I needed to feel a bit of summer. I needed a small town. What I didn’t know I needed was a big love story. This was perfect and escapist. A perfect read to make you feel good and characters to swoon over. Can’t wait for the show now.
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Reviewed in the United States on May 30, 2026
★★★★★ 5
Heartfelt and Nostalgic
Format: Paperback
What can I say to effectively capture the beauty, sweetness, and depth of this story?
Sam and Percy’s story is sweet and nostalgic, and it made me feel like I was a teenager again right along with them. It brought back memories of my own teenage years spent camping at various lakes with family and friends; memories I hadn’t thought about in awhile.
Barry’s Bay is a character in its own right as well, and I had such a vivid picture in my mind of what it must have looked like.
There were moments when I laughed out loud, and moments that made me cry. The exploration of guilt and what it does to a person and the ones they love was so emotional and real.
And the sweetness and love between Percy and Sam, despite all their mistakes and miscommunications, is something that will stick with me for a long time.
There is so much heart in this story. I love a good friends-to-lovers romance, and have read quite a few, but this is easily one of the best.
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Reviewed in the United States on April 10, 2026
★★★★★ 4
Cute little read
Format: Paperback
I thought this book was a good quick read!
Plot: 4⭐️ I won’t spoil it but there is a trope I wasn’t fond of in this toward the end of the book, BUT it’s a very realistic response to the situation. (I am not making it okay in ANY means). I do wish there would have been a little more fun memories between them as friends.
Characters: I think Carly did a great job keeping the characters realistic. Yes the FMC parents had some money but it was a refresher that nobody was spoiled and the MMC earned his way into medical school.
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Reviewed in the United States on May 20, 2026
★★★★★ 5
John Candy References!
Format: Kindle
Persephone is thirty years old and she just got dumped. She didn’t really care, he didn’t mean much to her and she never really let him in, even after seven months. She gets a phone call that has her racing back to her past, the small town of Barry’s Bay, and back into the life of the one who got away… Sam Florek.
For six summers Percy and Sam were inseparable. The friendship naturally blossomed and grew into something more and he became the man she never wanted to live without, until it fell apart in a splash.
Percy returns for Sam’s mothers funeral and all the feelings come rushing back, their connection burning as brightly as it had twelve years ago. But Percy has a secret, a reason for why she broke up with him, and until she tells him, they can never be together.
Told in dual timelines, we unravel the mystery of the once in a lifetime love story between two people who were as fated as a couple could be.
First and foremost, there are not one but TWO John Candy references in this book. He is a late Canadian actor who was popular in the 80s. Most will know him as the Polka Player from home alone but I know him from so much more. Trust me, he deserves this paragraph of recognition and I praise the author for including him as he is slowly being forgotten.
Now onto the story.
I loved it. No ifs ands or buts about it. I absolutely love this story. It is a dual timeline, second chance romance and I think it got me out of my reading slump. I finished it in less than 2 days and couldn’t put it down.
The history of the characters, watching them slowly fall in love and come to terms with their feelings. Seeing how they struggle over the long distances and other romances that pop up. It was so well written and it felt like I was watching two people I knew in real life fall for each other. It was so realistic , even the lows had me tearing up but remaining hopeful.
The twist, the reason why they broke up, was predictable. I saw it coming not long into the book but it didn’t take away from the heartache I felt when it was revealed.
I enjoyed that we also got to explore relationships outside of the main love interest. We got to know Percy’s friends and how they interacted with Sam too which was a nice break from the romance and gave depth outside of the love interest.
Great book and I’m so thankful it got recommended to me.
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Reviewed in the United States on March 24, 2023