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Description
PC-12 Cell LysateProduct Specification Host Rat Concentration 2 mg ml Physical Appearance Liquid Storage Buffer Supplied in SDS Sample Buffer: 50 mM Tris HCl (pH 6. 8 at 25C), 2% w v SDS, 10% glycerol, 1% v v Mercaptoethanol, 0. 01% w v bromophenol blue Stability & Storage 20 C for 1 months under sterile conditions; 80 C for 24 months under sterile conditions. Please avoid repeated freeze thaw cycles. Background The PC 12 cell line, derived from rat adrenal
Product Specification
| Host | Rat |
| Concentration | 2 mg/ml |
| Physical Appearance | Liquid |
| Storage Buffer | Supplied in SDS Sample Buffer: 50 mM Tris-HCl (pH 6.8 at 25°C), 2% w/v SDS, 10% glycerol, 1% v/v β-Mercaptoethanol, 0.01% w/v bromophenol blue |
| Stability & Storage | -20 °C for 1 months under sterile conditions; |
Background
The PC-12 cell line, derived from rat adrenal pheochromocytoma, is one of the most classic and widely used cell models in neuroscience research. These cells can be induced to differentiate into sympathetic neuron-like cells and extend neurites under the stimulation of nerve growth factor (NGF), making them highly suitable for studying: • The molecular mechanisms of neuronal differentiation and neurite outgrowth. • Neurotransmitter synthesis, storage, and release (particularly catecholamines). • Neuronal signal transduction pathways (e.g., neurotrophic factor signaling, MAPK/ERK pathways). • Neurodegenerative diseases (such as Parkinson’s disease and Alzheimer’s disease) as cellular models and related protein expression studies. • Neurotoxicity and screening of neuroprotective drugs.
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