Recombinant Human Eotaxin-3/CCL26 (Human Eotaxin-3/CCL26) _ 90971ESEotaxin 3, also named CCL26 or SCYA26, is a novel human CC chemokine. The eotaxin subfamily of CC chemokines consists of eotaxin 1 CCL11, eotaxin 2 CCL24 and eotaxin 3 CCL26. Eotaxin 3 CCL26 has been shown to be expressed by several different cell types, including basophils, dendritic cells, smooth muscle cells, epithelial cells and fibroblasts. Interleukin (IL) 4 is the main inducer for eotaxin 3 expression, whereas eotaxin 1 is up regulated by IL 4

mast cells

IL-10 inhibits the expression of pro-inflammatory cytokines such as IL-1 and TNF-α

also known as Intestinal Trefoil Factor (ITF) and P1

Targeting MDK Abrogates IFN-γ-Elicited Metastasis inCancers of Various Origins

The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1 ng/mL

and in pathological processes such as tumor growth

Molecular Weight Approximately 12 kDa under reducing conditions

Approximately 23

but can penetrate the cell membrane of late apoptotic and necrotic cells and make the nucleus red

such as T cells and natural killer cells

[6] Wang Y

Published 2020 Jun 12